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atenolol
GENERIC
NAME: atenolol
BRAND NAME:
Tenormin
DRUG CLASS
AND MECHANISM: Atenolol is a beta-adrenergic blocking
agent. Atenolol blocks the action of the sympathetic
nervous system, a portion of the involuntary nervous
system. The sympathetic nervous system stimulates the
pace of the heart beat. By blocking the action of these
nerves, atenolol reduces the heart rate and is useful in
treating abnormally rapid heart rhythms. Atenolol also
reduces the force of heart muscle contraction and lowers
blood pressure. By reducing the heart rate and the force
of muscle contraction, atenolol reduces heart muscle
oxygen demand. Since angina occurs when oxygen demand of
the heart exceeds supply, atenolol is helpful in
treating angina.
PRESCRIPTION: yes
GENERIC
AVAILABLE: yes
PREPARATIONS: Tablets: 25 mg, 50
mg, 100 mg.
STORAGE:
Tablets should be stored at room temperature in a
tightly closed container.
PRESCRIBED
FOR: Atenolol is prescribed for patients with high blood
pressure (hypertension). It is also used to treat chest
pain (angina pectoris) related to coronary artery
disease. Atenolol is also useful in slowing and
regulating certain types of abnormally rapid heart rates
(tachycardias). Other uses for atenolol include the
prevention of migraine headaches and the treatment of
certain types of tremors (familial or hereditary
essential tremors).
DOSING:
Should be taken before meals or at bedtime.
DRUG
INTERACTIONS: Atenolol can aggravate breathing
difficulties in patients with asthma, chronic
bronchitis, or emphysema. In patients with existing slow
heart rates (bradycardias) and heart blocks (defects in
the electrical conduction of the heart), atenolol can
cause dangerously slow heart rates, and even shock.
Atenolol reduces the force of heart muscle contraction
and can aggravate symptoms of heart failure. Calcium
channel blockers, and digoxin (Lanoxin) can cause
lowering of blood pressure and heart rate to dangerous
levels when administered together with atenolol. In
patients with coronary artery disease, abruptly stopping
atenolol can suddenly worsen angina, and occasionally
precipitate heart attacks. If it is necessary to
discontinue atenolol, its dosage can be reduced
gradually over several weeks. Atenolol can mask the
early warning symptoms of low blood sugar
(hypoglycemia), and should be used with caution in
patients receiving treatment for diabetes. It is not
habit forming.
PREGNANCY:
Atenolol may cause harm and growth retardation in the
fetus when given to pregnant women.
SIDE EFFECTS: Atenolol is
generally well tolerated, and side effects are mild and
transient. Rare side effects include abdominal cramps,
diarrhea, constipation, fatigue, insomnia, nausea,
depression, dreaming, memory loss, fever, impotence,
lightheadedness, slow heart rate, low blood pressure,
numbness, tingling, cold extremities, sore throat, and
shortness of breath or wheezing.
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